Transduction of Neuronal Signals by Brain Macroglial Cells: Implications for Neuronal Function
Grant number: DP0770955
Abstract
Study of mechanisms regulating brain cell (neuron and glial) communication is essential for understanding of normal brain function and transformations that occur in neurodegenerative states and age-related disorders. Mechanisms underlying neuron-glia communication are not well understood. By combining cell physiology, digital imaging technologies, and genetically designed and delivered molecules we will enhance our understanding of this brain cell communication and critical roles played by intracellular calcium. This will enhance international competitiveness of Australian biological research and provide novel insight of glial function in neurodegeneration and potential for specific therapeu..
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